The Hong Laboratory focuses on understanding the regulation and remodeling of membrane microdomains of cardiomyocytes during heart failure progression. We study how cardiomyocyte surface microdomains are organized to concentrate ion channels and signaling proteins for proper function and regulation in normal and failing hearts. The research interested includes the mechanisms of scaffolding protein and cytoskeleton-based maintenance of membrane structures and subdomains important in calcium signaling, turnover mechanisms of microdomains, and the mechanisms of heart failure progression. The goal is to identify, at the bench, new molecular and cellular targets that can be translated to develop new therapeutic tools for clinical management of heart failure.
Meet the Hong Lab Team
Mentorship and Training
Dr. Hong has a strong commitment to mentoring the next generation of scientists and physician-scientists.
More than 100 publications were authored by trainees or junior faculty under his mentorship and many of them were supported by competitive career development training grants. Ten of his mentees have moved on to independent faculty positions.
For translational and basic science research job opportunities please contact Tingting.Hong@pharm.utah.edu(please include your CV and potential referees).
